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15 Best Airbnbs in South Carolina, USA

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Endless coastline, charming historic towns, and gorgeous inland scenery await in the diverse state of South Carolina. With its historic architecture, antebellum attractions, and unique local culture, this attractive tourist destination is often referred to as a living museum. 

To help kickstart your search for the perfect accommodation, we’ve created the following list of the best Airbnbs in South Carolina. All of the rentals listed are presided over by superhosts – hosts with a proven track record of providing outstanding hospitality. Most of the listings are also appointed with an exceptional selection of modern amenities such as Wi-Fi, TV, and air-conditioning. 

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Serene Cottage

First on our list is an Airbnb in Charleston, South Carolina, with a gorgeous courtyard and a heated pool. The property also boasts Airbnb Plus status, meaning its beautiful design and high quality amenities have been verified through in-person inspection. 

The light-filled villa offers one bedroom with a king-size bed, one full bathroom, and one powder room. Both the living room and the second-floor bedroom are surrounded by picturesque windows that make the space beautiful and bright. The small and charming home also comes with a small kitchen and a dining table for two. All around the home, you’ll find lush gardens and impressive stonework with a fountain pond in front and a heated inground pool in the back. 

Located in the trendy neighborhood of Cannonborough Elliotborough, this South Carolina Airbnb is surrounded by local eateries, indie boutiques, bakeries, and vintage stores. 

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Related: 15 Best Airbnbs in Charleston, SC

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The Majestic Treehouse

For a one-of-a-kind stay among the treetops, take a trip to this tranquil forested property under the Blue Ridge Mountains. 

The treehouse is filled top to bottom with antique furnishings, authentic fine china, and stunning hardwood details. Furnished with a king-size bed with a regal antique frame, the studio space makes a magical romantic getaway for a couple. A crystal chandelier hangs from the soaring ceilings and full walls of windows bring the outside in. There is a small kitchenette and coffee bar with a retro-style breakfast maker, and a two-person dining table sits next to a cozy fireplace. Guests have access to an indoor half bathroom with hot water as well as a private outdoor shower with two rain-style showerheads. Additional features include a chest of antique board games, a classic record player, a vintage guest book, and a pair of plush robes. 

Outside, you’ll find a romantic rope swing bed, a cozy firepit area, and a top deck with comfy loungers. 

Set on 40 acres of oak-filled forest, stunning gardens, and lush organic farmland, this award-winning treehouse in South Carolina is one of the state’s most popular Airbnbs. The property comes with miles of trails for hiking, jogging, and mountain biking and a few private creeks. 

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Luxury Treehouse With a Hot Tub

This mid-century modern treehouse is another great option for a unique vacation rental in South Carolina. 

The ultra-modern interior features whitewashed wood planks, floor-to-ceiling windows, and a unique geometric chandelier. Although the studio space is small, it is well equipped with all of the basic necessities – and then some. There is a small full kitchen with granite countertops, a dishwasher, and a retro refrigerator, and guests have access to both a full bathroom and a luxurious outdoor shower. The cozy sitting area boasts a wall-mounted TV and a modern indoor fireplace, behind which you’ll find a plush queen-size bed. 

Tucked away on a private wooded property, the treehouse is surrounded by a spacious deck, well-manicured gardens, and glimmering string lights. Guests also have access to a cozy firepit area, a stainless-steel grill, and a luxurious outdoor hot tub. 

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Romantic Cottage Near Pickens

If you’re on the hunt for a romantic mountain getaway, look no further — Superhost Patrick has the perfect place for you. A trail of fairy lights illuminates the stone path through the forest to this beautiful one-bedroom cabin. Enjoy ample privacy in this serene setting, and spend your evenings fireside under a blanket of stars.

Upon entering the home, guests will find a contemporary-rustic space featuring vintage furnishings, exposed timber frames, and elegant décor reminiscent of the French countryside. Start your day with a steaming cup of coffee on the front porch, where a bistro table and lounge chairs await. Afterwards, make your way to the bathroom for an indulgent bubble bath in the rustic clawfoot tub while listening to records on the vintage vinyl player.

In the bedroom, a comfortable king-size bed and two lounge chairs provide the ideal spot to relax with a book. A small kitchenette is also available, complete with a microwave, Nespresso coffee maker, and two-person breakfast bar. If you’d prefer to be catered to, Patrick also offers breakfast delivery upon request. When the adventurous mood strikes, explore one of the many hiking trails nearby — Table Rock State Park and Lake Keowee are just a 20–25 minute drive away. 

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Breathtaking Lakefront Treehouse on Lake Greenwood

This South Carolina Airbnb has it all—from outstanding amenities to an idyllic setting and a unique layout. The treehouse on Lake Greenwood offers a memorable getaway for couples, all set in a spectacular one-bedroom raised retreat. Enjoy romantic evenings on the balcony, soaking in the private hot tub, or cuddling on the porch’s queen-size swing bed. A private dock offers an excellent spot for fishing, swimming in the lake, or simply enjoying the scenery while lounging in Adirondack chairs. Superhost Kristin even provides fishing poles and tackle! Outside, you’ll also find a hammock, a patio dining set, and a breakfast bar.

Inside, the treehouse boasts an airy contemporary-country motif with high-end finishes, elegant French décor, and antique French doors imported from Turkey. Retreat to the bathroom’s luxurious clawfoot tub for a romantic bubble bath, or head to the kitchen’s dining table for a board game night. The open-concept layout includes a gorgeous full kitchen with a butler’s station and solid oak countertops. Visitors can rest easily in the plush king-size bed, which features a French-inspired mahogany bed frame. Other standout features include automatic blinds, a vintage vinyl player, and a washer and dryer.

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Related: 15 Best Airbnbs in Hilton Head, SC

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Waterfall Getaway

Situated on over 90 acres of wooded property in the foothills of the Appalachian Mountains, this cliffside Airbnb offers a remote stay overlooking a rushing waterfall. 

With no TV or internet, the home provides a rustic glamping experience ideal for nature lovers looking to unplug and unwind. Floor-to-ceiling windows throughout the home allow you to take advantage of the stunning waterfall views, even when you’re cozy in bed or cooking a meal in the full kitchen. There is one full bathroom and two bedrooms with double beds, making the space suited for up to four guests. The focal point of the living room is the large brick fireplace, and the home’s unique architecture makes the common areas feel exceptionally spacious and airy. 

This unique Airbnb in South Carolina is completely secluded with no neighbors in sight. There are plenty of opportunities for exploring, hiking, and kayaking, and the nearest urban attractions are nine miles away in downtown Toccoa. 

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South Beach Cottage

This Airbnb in Myrtle Beach, South Carolina, makes the perfect shore retreat for large families and groups of friends. 

Up to 10 guests can stay in the four-bedroom, 3.5-bathroom home, which is furnished with two king-size beds, two queen-size beds, and a pullout couch in the living room. The cottage is decorated with beach-themed décor and offers a full kitchen with granite countertops and top-of-the-line appliances. Additional amenities include a dedicated workspace, laundry facilities, and a dishwasher, and guests can park for free on the premises. 

Located just steps away from the Atlantic Ocean, this beach house in South Carolina overlooks Ocean Boulevard and comes with access to an outdoor pool. There are several fun attractions nearby, including Tanger Outlets, Splashes Waterpark, the boardwalk, and minigolf. 

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Related: 15 Best Airbnbs in Myrtle Beach, SC

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Private Beach Paradise

Another charming South Carolina Airbnb on the coast is this private bungalow in Folly Beach. 

Originally built in the 1940s, the gorgeous accommodation has been completely updated to include modern appliances, stylish furniture, and original artwork. The colorful interior is bright and spacious and offers an open-concept living area with a high-end full kitchen, bench-style seating, several comfy couches, a wall-mounted TV, and a convenient desk space. There are two bedrooms with queen-size beds and one full bathroom, and guests also have access to a private outdoor shower. The home is surrounded by a wrap-around porch decorated with luscious plants and glimmering string lights, and the rental comes with a stainless-steel grill and plenty of outdoor seating. 

Situated just two blocks away from the shore, this Airbnb in Folly Beach, South Carolina, is also within walking distance of the restaurants, bars, and markets on Center Street. 

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The Wren Guesthouse

For a South Carolina Airbnb with a historic setting and a gorgeous courtyard, check out this private guesthouse in Beaufort. 

Nestled on a quiet uptown street, the home offers one bedroom with a queen-size bed and an en suite bathroom, making it ideal for a solo traveler or a couple. The open-concept layout boasts a spacious sitting area and a full kitchen, and grand windows in the living room expose beautiful views of the surrounding garden. Special features include stylish wood furnishings, a sliding barn door leading to the bathroom, and attractive splashes of color throughout the home. Luscious plants and eye-catching bistro lights fill the surrounding courtyard, which offers ample privacy. 

This charming Airbnb in Beaufort, South Carolina, shares the property with a historic 1920s home and is just two blocks away from the river, shops, galleries, and waterfront eateries. 

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Tropical Tiny House

Few Airbnbs in South Carolina offer the creative atmosphere and adorable interior of this Fountain Inn tiny house. 

With Spanish tiles, hand-painted walls, and a custom design, the rental was created to represent a combination of Miami and Mexico. There are five skylights and a variety of desert plants that make the space light and lively, and light pink walls add to the cheerful ambiance. Although the space is tiny, it boasts a very efficient layout with two separate bedrooms furnished with queen-size beds. Feel free to sit back and relax in front of the TV in the cozy sitting area or enjoy a meal with the convenient bar-style seating. There is even a modern full kitchen with an oven and a stove, and the full bathroom features a walk-in shower and a tropical mural. Outside, you’ll find a furnished patio with a decorative surfboard, a hanging chair, and more desert plants. 

Tucked away in the woods, this short-term rental in South Carolina is about 20 minutes away from downtown Greenville and just a few miles from local bars, restaurants, and outdoor excursions. Guests can head over to Cucina 100 for delicious brick oven pizza or make a day trip to Barefoot Acres, where they offer rope courses, zip lines, nature trails, and more. 

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The Barn on Blu Grace Farm

Spend a weekend—or a week—surrounded by highland cows, horses, and alpacas at this unique pet-friendly apartment rental on Blu Grace Farm near Marion. This highly rated Airbnb in South Carolina is only an hour’s drive from Myrtle Beach and offers a charming escape for couples or families. The best part? You can even pet and feed the livestock during your stay!

The “barndo,” as Superhost Brook calls it, features a modern-rustic motif with whitewashed wood-paneled walls, country-themed décor, and antique furnishings. The home also has an open-concept layout with a queen-size bed and a well-stocked kitchenette that includes a mini-fridge, microwave, water dispenser, and coffee maker. A sofa bed creates a small living area, and an air mattress can be set up to make this rental suitable for up to five people. Perhaps the most charming feature in the apartment is the shower, crafted from a repurposed galvanized metal bucket—a lovely, creative touch.

A custom barn-wood Dutch door opens to the repurposed stables, home to the charming barn apartment and a wooden six-person dining table set inside one of the stalls. At either end of the barn, two patios feature rocking chairs, fairy lights, a cozy couch, and a fire pit. In the yard, kids can play freely on the custom-built playground or help feed the cows.

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Romantic Mountain Treehouse

For an Airbnb in South Carolina with a luxurious interior and gorgeous natural scenery, check out this Mountain Rest treehouse that makes the perfect romantic getaway. 

With no Wi-Fi or TV in the cabin, this is a great choice for travelers looking for a break from digital distractions. Indoor entertainment options include a basket of games, playing cards, and a vintage record player. The king-size bed sits below a vintage crystal chandelier and boasts a custom-built live edge frame, a Tuft and Needle mattress, and a white canopy that makes the sleeping area very romantic. One of the cabin’s decks can be accessed through the French door right across from the bed, and guests have access to a cozy indoor seating area, a kitchenette, and a dining table for two. Premium wood finishes make the space elegant and warm, and the half bathroom boasts a custom sliding wooden door. 

Outside, you’ll find two dining spaces, an electric grill, a summer shower, a firepit, and a lower deck with a fun string game. The firepit area comes with firewood and a basket of s’mores supplies, and one of the best features of this rental is the gorgeous bridge that leads to the completely private napping deck. Guests can also explore the plethora of surrounding waterfalls and hiking trails, Stumphouse Tunnel, Stumphouse Mountain Bike Park, and Issaqueena Falls. 

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The Elmwood Retreat

Originally built in 1905, this gorgeous Airbnb in Columbia, South Carolina, is listed on the National Register of Historic Places. 

With 2.5 bathrooms, a master bedroom on the main floor, and three more bedrooms on the second floor, the home can sleep up to eight guests. Granite countertops, elegant chandeliers, and high-end linens are just a few of the many premium features included with this rental. The main floor is simple but gorgeous with bright white and soft grey finishes, an incredible chef’s kitchen, an ultra-comfy living room, and a formal dining space with an indoor fireplace. The master bedroom boasts a washer and dryer and gorgeous stained-glass accents. Guests also have access to a small office space with a desk and a USB light stand. Feel free to relax in the white rocking chairs on the side porch or take a stroll along the historic tree-lined street. 

Situated in the historic Elmwood Park neighborhood, this South Carolina Airbnb is surrounded by a combination of vibrant downtown attractions, old homes, and gorgeous gardens. Main Street is just a short walk away from the home, as is the Museum of Art, the State Museum, and Colonial Life Arena. 

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Shem Creek Guesthouse

With a convenient Mount Pleasant location, high-end amenities, and safe and quiet surroundings, this vacation home for rent in South Carolina is one that you definitely won’t want to miss. 

The guesthouse is set on the same property as the host’s main home but offers a completely private stay with its own driveway, a privacy gate, and a private furnished patio. Inside, there is one bedroom with a king-size bed and a Smart TV as well as a full bathroom with a walk-in shower. The spacious living room features a second TV and a sleeper sofa, and there is a full kitchen and a separate laundry closet for longer stays. 

Shem Creek, where guests can enjoy an impressive array of fun watersports, is located directly behind the property. The beach at Sullivan’s Island is also just a few miles away, and the restaurants and shops of Coleman Boulevard are within walking distance of the guesthouse. 

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Enchanting Cottage on the Savannah River

Spend your days swimming and fishing in the Savannah River at this gorgeous one-bedroom waterfront rental near Hardeeville. This cozy, pet-friendly cottage offers an ideal two-acre private setting surrounded by Spanish moss, mature trees, and a trickling creek. The site also has roots in the Civil War, with remnants of an old shipyard on-site and an 18th-century graveyard down the road. Coupled with its cozy country interior, this home is a true Southern belle.

Visitors can bask in the sun on the private dock, complete with a four-person dining set, an umbrella, and two Adirondack chairs. When the mosquitoes come out, retreat to the screened-in porch and unwind under dazzling fairy lights and two outdoor fans. There’s also a barbecue and a fire pit in the fenced yard.

Inside, the home features wall-to-wall, floor-to-ceiling windows on two sides, offering plenty of natural light and beautiful river views. The living room is furnished with a Smart TV, board games, a pullout couch, and a library of books. Guests can easily prepare meals in the full kitchen, which includes stainless steel appliances, a blender, and a complimentary breakfast basket with all the fixin’s. When it’s time to unwind, retreat to the mezzanine bedroom’s king-size bed for a restful night’s sleep.

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Hopefully this list is helpful and you’re able to find the best Airbnb rental in South Carolina for your dream vacation. 

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